Scientists have identified a gene that may play a protective role in preventing heart disease. Their research revealed that the gene, called MeXis, acts within key cells inside clogged arteries to help remove excess cholesterol from blood vessels.
Erectile dysfunction (ED) is a major public health problem. Men being treated for cardiovascular risk factors such as high blood pressure and high cholesterol are at increased risk of developing ED and often consider this condition a side effect of their medications. However, a new study into the effects of cholesterol-lowering statins and blood-pressure lowering candesartan/HCTZ concludes that these medications do not negatively affect erectile function.
Scientists discovered that boosting mice's cholesterol levels spurred intestinal stem cells to divide more quickly, enabling tumors to form 100 times faster. The study identifies a molecular pathway that could serve as a new drug target for colon cancer treatment.
Fewer than one in 100 stroke survivors meet all of Life's Simple 7 goals for ideal cardiovascular health identified by the American Heart Association. Moreover, the proportion who fail to meet almost all of the criteria is on the rise, according to preliminary research.
Massive banks of genetic information are being harnessed to shed new light on modifiable health risks that underlie common diseases. Researchers have pioneered a method to integrate data from multiple large-scale studies to assess risk factors such as body mass index (BMI) and cholesterol levels, and their association with diseases including type two diabetes and heart disease.
A risk score based on multiple genetic differences, or polygenic test, predicted significantly more cases of early heart disease than standard tests for single genetic defects. The polygenic test predicted a high risk for early-onset heart disease in 1 out of 53 individuals, compared to 1 in 256 for the most frequent single genetic defect.
Multiple Sclerosis is a chronic inflammatory disease of the central nervous system, in which the immune cells attack myelin sheaths. Regeneration of myelin sheaths is necessary for patients to recover from MS relapses. Nevertheless, the ability to regenerate decreases with age.
Given the ever-increasing obesity epidemic, researchers have discovered a promising developing drug that has been shown to selectively shrink excess fat by increasing fat cell metabolism. The drug significantly reduces body weight and blood cholesterol levels without lowering food intake in obese mice, according to a recent study.
In a direct comparison study, researchers have added to evidence that a newer method of calculating so-called 'bad cholesterol' levels in the blood is more accurate than the older method in people who did not fast before blood was drawn.
Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. For multiple sclerosis, specifically, increasing cholesterol synthesis gene expression in astrocytes of the spinal cord can be a pathway to repair nerves that affect walking.
Substituting one to two servings of animal proteins with plant proteins every day could lead to a small reduction in the three main cholesterol markers for cardiovascular disease prevention, a new study suggests.
New research explains how an enzyme acts as a kind of thermostat that responds to and adjusts levels of cholesterol in the cell. This insight could lead to new strategies for combating high cholesterol.
Heart disease and fatty clogs in the arteries go hand in hand. But new evidence suggests the fatty molecules might come not only from what you eat, but from the bacteria in your mouth, scientists report. The research may explain why gum disease is associated with heart trouble.