Efforts to reverse the nation's opioid epidemic remain beset by the stigma associated with drug use, a group of researchers write in a year-end review. The researchers emphasize the need for the American health care system to embrace medications such as methadone to treat opioid use disorder, provide addiction treatment in primary care clinics and develop non-addictive alternatives for chronic pain.
For the first time, scientists have solved the crystal structure of the activated kappa opioid receptor bound to a morphine derivative. They then created a new drug-like compound that activates only that receptor, a key step in the development of new pain medications.
Taking paracetamol during pregnancy may impair the future fertility of female offspring, according to a new review. The article reviews three separate rodent studies that all report altered development in the reproductive systems of female offspring from mothers given paracetamol during pregnancy, which may impair their fertility in adulthood.
A new study examines what may cause chronic back pain in runners and the exercises to help prevent it. The study suggests that runners with weak deep core muscles are at higher risk of developing low back pain. And, unfortunately, most people's deep core muscles aren't nearly as strong as they should be.
The most common type of tumor found in the kidney is generally quite small (less than 1.5 in). These tumors are usually found by accident when CAT scans are performed for other reasons and the serendipitous finding poses a problem for doctors.