Opioid pain relievers can be extremely effective in relieving pain, but can carry a high risk of addiction and ultimately overdose when breathing is suppressed and stops. Scientists have discovered a way to separate these two effects -- pain relief and breathing -- opening a window of opportunity to make effective pain medications without the risk of respiratory failure.
If you visit your family doctor with low back pain (LBP), you may be surprised at the treatment options they suggest now. Recent changes to major international guidelines for the management of LBP mean that general practitioners (GP) are now unlikely to recommend pain medicines which were previously the go-to treatment. Instead of pain medicines, GPs might suggest non-medicinal approaches including yoga, mindfulness and various types of physiotherapy and psychological therapies.
Patients who go to the ER with chest pain often receive unnecessary tests to evaluate whether they are having a heart attack, a practice that provides no clinical benefit and adds hundreds of dollars in health-care costs, according to new research. CT scans and cardiac stress tests are overused in the ER for patients with chest pain and provide no information to determine whether a patient is in the midst of a heart attack.
Women who undergo vaginal delivery often do not require opioids to manage pain after hospital discharge, concludes a study. In addition, the quantity of opioids prescribed to women after cesarean delivery can be less than currently prescribed, say the authors.
Inflammatory bowel disease is common amongst older people and there are big differences in the choice of treatment for different age groups. Patients over the age of 60 often receive cortisone drugs instead of more modern medicines that target the immune system.
Scientists have discovered why pain from the head and face can be more disruptive, and more emotionally draining, than pain elsewhere in the body. The team found that sensory neurons from the head and face are wired directly into one of the brain's principal emotional signaling hubs, while sensory neurons from the body are connected only indirectly. The results may pave the way toward more effective treatments for chronic head pain.
By teaching patients better strategies for coping with chronic pain, cognitive behavioral therapy (CBT) is a valuable treatment alternative for the millions of Americans taking opioids for noncancer pain, according to an article.
Researchers have found distinct molecular signatures in two brain disorders long thought to be psychological in origin -- chronic fatigue syndrome (CFS) and Gulf War Illness (GWI). In addition, the work supports a previous observation of two variants of GWI.
Scientists propose a list of foods that can help patients manage rheumatoid arthritis, based on a new comprehensive review of foods with proven long-term beneficial effects on inflammation, joint stiffness and pain, joint destruction and oxidative stress.
After suffering repeated bouts of debilitating Clostridium difficile infections, many patients significantly change their behaviors, but some precautions may do little to prevent future infections, according to a first-of-its-kind study.
An analysis of the medical records of patients treated at Massachusetts General Hospital for an often-mysterious condition involving damage to small nerve fibers supports the hypothesis that some cases are caused by autoimmune disease and also identifies the first effective treatment option.
For adults coming to the emergency department for arm or leg pain due to sprain, strain, or fracture, there was no difference in pain reduction after two hours with ibuprofen-acetaminophen vs three comparison opioid-acetaminophen (paracetamol) combinations.