More than 700,000 Americans were hospitalized due to illnesses associated with the seasonal flu during the 2014-15 flu season, according to federal estimates. A radical new approach to vaccine development may help lower that figure for future flu seasons.
Seasonal flu viruses continually undergo mutations that help them evade the human immune system, but some of these mutations can reduce a virus's potency. According to new research, certain mutations in the genome of influenza A may help counteract the weakening effects of other mutations.
Scientists have shown in the laboratory that an inhibitor can be developed to break down the herpes virus. Kaposi's sarcoma-associated herpes virus, or KSHV, is one of two viruses known to cause cancer in humans.
It is easier to spread the influenza virus (flu) than previously thought, according to a new study. People commonly believe that they can catch the flu by exposure to droplets from an infected person's coughs or sneezes or by touching contaminated surfaces. But, new information about flu transmission reveals that we may pass the flu to others just by breathing.
By analyzing immune cells of children who came to the emergency department with flu symptoms, researchers found that the suite of genes these early-response cells expressed was shaped by factors such as age and previous exposures to viruses. Better understanding how early infections influence long-term immune response has implications for the diagnosis and treatment of young patients who suffer from acute respiratory tract infections.
Researchers have discovered how the innate immune system, which responds more generally to dangers detected in the body, can be trained to 'remember' past threats and respond more robustly to future challenges.
Recent advances in brain imaging have enabled scientists to show for the first time that a key protein which causes nerve cell death spreads throughout the brain in Alzheimer's disease -- and hence that blocking its spread may prevent the disease from taking hold.
As flu season swings into high gear, a new poll suggests nursing homes and other long-term care facilities should be doing more to get their staff and patients vaccinated before it's too late. Nearly three-quarters of people over age 50 surveyed in a new poll say all staff in such facilities should definitely be required to get the flu vaccine. More than 60 percent say that patients in such facilities should definitely get vaccinated too.
Nearly a century after the influenza pandemic of 1918–1919 ravaged communities worldwide, the threat of another pandemic looms large as the scientific and global health communities find ways to prepare for, and battle, future outbreaks.
In the not-too-distant future, nanoparticles delivered to a cancer patient's immune cells might teach the cells to destroy tumors. A flu vaccine might look and feel like applying a small, round bandage to your skin. These are examples of how innovative biomaterials could enhance vaccines against HIV and other infectious diseases and immunotherapies for patients with cancer or dampen responses in autoimmune disorders, allergies and transplanted organ recipients.
Scientists have predicted which H3N2 variants would become 'vaccine resistant', and this prediction has been confirmed during the 2017 Australian flu season. The results published suggest that the current flu vaccine will work better during the 2018 US flu season than the 2017 Australian flu season.
Lactic acid bacteria, commonly used as probiotics to improve digestive health, can offer protection against different subtypes of influenza A virus, resulting in reduced weight loss after virus infection and lower amounts of virus replication in the lungs, according to a new study.